Related Experiment Video
Updated: Jul 15, 2026

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
Published on: April 19, 2017
Phomaligol J, a New Cyclohexenone With Antibacterial Activity From a Pufferfish-Associated Fungus Aspergillus
Wang-Yang Du1,2, Hui-Fang Wang1,3, Ruo-Nan Sun1,4
1Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, Shandong, China.
Abstract:
A new cyclohexenone, phomaligol J (1), along with nine known compounds (2-10) were isolated from the liquid culture of the pufferfish-associated Aspergillus austwickii collected from Yangma Island, Yantai. Their structures were determined by extensive spectroscopic data analysis, high resolution electrospray ionization mass spectrometry (HRESIMS), electronic circular dichroism (ECD), and the comparison with reported data in the literature. In bioactivity, all isolated compounds were evaluated for antibacterial activity against 12 bacterial strains. Notably, compound 1 exhibited moderate antibacterial activity against Staphylococcus aureus with a minimum inhibitory concentration (MIC) value of 40 µg/mL.
More Related Videos
09:52Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
09:21Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.
Published on: February 15, 2019
Related Concept Videos
Gene Regulation in Microbial Communities: Quorum Sensing
Bacterial Phylum Planctomycetes
Bacterial Phylum Actinobacteria
Fungal Phylum Ascomycota
Production of Antibiotics
Antifungal Agents