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Updated: May 24, 2025

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An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
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Positional mitral regurgitation: a dynamic phenomenon.
Marta Leite1, Eduardo Vilela2,3, Jorge Oliveira2
1Cardiology Department, Unidade Local de Saúde Gaia/Espinho, 4434-502, Vila Nova de Gaia, Portugal. martaleite95@gmail.com.
The International Journal of Cardiovascular Imaging
|March 5, 2025
Summary
Severe mitral regurgitation (MR) in a patient with dilated cardiomyopathy improved with upright positioning. This highlights how body position significantly impacts MR severity and symptoms.
Area of Science:
- Cardiology
- Cardiovascular Imaging
Background:
- Mitral regurgitation (MR) is a complex valvular heart disease.
- Positional changes and physical stress can dynamically alter MR severity.
Observation:
- A 74-year-old woman with dilated cardiomyopathy presented with severe positional MR.
- Echocardiography revealed significant leaflet tethering and restricted mitral valve mobility.
Findings:
- Upright positioning markedly reduced MR severity and associated symptoms.
- Hemodynamic factors play a crucial role in the clinical manifestation of positional MR.
Implications:
- Understanding positional effects is vital for accurate MR assessment.
- This case emphasizes the need for comprehensive evaluation considering patient positioning.

