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Hyperbaric oxygenation in peripheral ischaemic lesions in infants
Archives of Disease in Childhood
|April 1, 1985
Summary
Disseminated intravascular clotting in infants can cause limb necrosis. Hyperbaric oxygen therapy helped halt the progression of tissue death in affected infants.
Area of Science:
- Neonatal Medicine
- Vascular Biology
- Hematology
Background:
- Acute peripheral arterial occlusion is a severe condition that can lead to limb gangrene.
- Disseminated intravascular clotting (DIC) is a serious disorder with potential vascular complications.
Observation:
- Three infants presented with distal limb discoloration (fingers and toes) due to DIC.
- The discoloration indicated acute peripheral arterial occlusion and progressing necrosis.
Findings:
- Repeated hyperbaric oxygenation (HBO) treatments were administered to the affected infants.
- HBO therapy led to regression of the demarcation line in the affected limbs.
- The progression of necrosis was halted following hyperbaric oxygenation treatments.
Implications:
- Hyperbaric oxygenation may be a viable therapeutic option for limb-threatening ischemia in infants with DIC.
- Early intervention with HBO could potentially prevent amputation and preserve limb function.
- Further research is warranted to establish optimal protocols for HBO in neonatal vascular emergencies.