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Identification of immunogenic outer membrane vesicle vaccine antigen components using a meningococcal protein

F Ramirez-Bencomo1, A Thistlethwaite1, V Viviani2

  • 1School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

Vaccine
|March 5, 2025
PubMed

Keywords:
Antigen microarrayBexseroMeningococcal diseaseNeisseria meningitidisOuter membrane vesicles (OMVs)Partial least squares regression (PLS)Vaccine antigens

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Complete Antigens
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Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
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Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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