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Updated: May 24, 2025
A Simple and Efficient Method to Isolate Macrophages from Mixed Primary Cultures of Adult Liver Cells
Published on: May 24, 2011
Macrophage therapy and liver regeneration: Results and perspectives
Nicolas Lanthier1, Laurent Spahr2
1Gastroenterology and hepatology, University hospitals of Geneva, Geneva, Switzerland; Service d'Hépato-gastroentérologie, Cliniques universitaires Saint-Luc, UCLouvain, Brussels, Belgium; Laboratory of Hepatogastroenterology, Institut de recherche expérimentale et clinique, UCLouvain, Brussels, Belgium.
Abstract:
The recent results of the study evaluating the impact of macrophage transplantation in cirrhosis with the aim of improving liver function open up a number of prospects. Although negative, fewer deaths were observed, as well as a favourable cytokine profile. This is in line with other results obtained in liver disease, notably through signalling and regeneration studies on human liver tissue. For the future, a number of questions need to be answered if we are to make progress in this fascinating field.
