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Related Concept Videos

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

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Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
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Esophageal Strictures-II: Clinical Features and Management01:26

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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Related Experiment Video

Updated: May 24, 2025

Iatrogenic Injury Recapitulated: Electroexcision Technique for Urethral Stricture Modeling in Rats
03:37

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Urethral Stricture Symptom and Impact Measure Validation Study.

Bryan B Voelzke1, Todd C Edwards2, Alex J Vanni3

  • 1Spokane Urology, Spokane, WA.

Urology
|March 5, 2025
PubMed
Summary
This summary is machine-generated.

A new patient-reported outcome measure, the Urethral Stricture Symptom and Impact Measure (USSIM), was developed and validated for men with urethral stricture disease. The USSIM demonstrates strong measurement properties for use in clinical and research settings.

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Area of Science:

  • Urology
  • Patient-Reported Outcomes
  • Psychometrics

Background:

  • Urethral stricture disease significantly impacts men's quality of life, affecting urinary and sexual function.
  • Existing outcome measures may not fully capture the patient experience of urethral stricture disease.

Purpose of the Study:

  • To develop and validate a disease-specific patient-reported outcome measure (PRO) for men with urethral stricture disease.
  • To ensure the measure is derived from the patient's perspective and reflects their experiences.

Main Methods:

  • Qualitative methods were used to construct the initial measure.
  • Psychometric evaluations, including internal consistency, validity, sensitivity to change, and test-retest reliability, were performed on the final instrument using preoperative and postoperative data.

Main Results:

  • The Urethral Stricture Symptom and Impact Measure (USSIM) consists of 10 items across three dimensions, assessing urinary and sexual function.
  • The USSIM demonstrated good internal consistency (Cronbach's alpha 0.8-0.82) and moderate to good test-retest reliability (ICC 0.74).
  • The measure showed adequate ability to discriminate between patients with different surgical outcomes and a skew toward improved function post-surgery.

Conclusions:

  • The USSIM is a validated instrument with strong measurement properties for assessing urethral stricture disease in men.
  • The USSIM is suitable for use in both preoperative and postoperative settings to evaluate patient outcomes.