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[Gynecomastia in boys before puberty].

H Descamps, J L Chaussain, J C Job

    Archives Francaises De Pediatrie
    |February 1, 1985
    PubMed
    Summary

    Gynecomastia in prepubertal boys is rare, with 16 cases studied. Most cases were idiopathic, showing slight, often unilateral breast enlargement that can resolve spontaneously.

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    Area of Science:

    • Pediatric Endocrinology
    • Adolescent Medicine
    • Endocrine Disorders

    Context:

    • Gynecomastia is uncommon in prepubertal boys, necessitating further investigation into its causes and presentation.
    • This study examines sixteen cases of prepubertal gynecomastia to understand its characteristics and potential etiologies.

    Purpose:

    • To report and analyze sixteen cases of prepubertal gynecomastia.
    • To investigate the association between gynecomastia and 11 hydroxylase deficiency with virilizing adrenal hyperplasia.
    • To characterize idiopathic prepubertal gynecomastia and explore potential underlying factors.

    Summary:

    • Sixteen cases of prepubertal gynecomastia were identified, with three linked to 11 hydroxylase deficiency and virilizing adrenal hyperplasia.
    • The remaining thirteen cases were classified as idiopathic, presenting as mild, often unilateral breast enlargement.
    • A significant proportion (5 of 16) of these cases exhibited spontaneous resolution within 3 to 12 months.
    • Hormonal investigations in idiopathic cases yielded normal results, precluding a clear physiopathological explanation.

    Impact:

    • Highlights the rarity and varied presentation of gynecomastia in prepubertal males.
    • Identifies a subset of cases associated with specific endocrine disorders, aiding in diagnosis.
    • Characterizes idiopathic cases, suggesting a benign and self-limiting course for many.
    • Underscores the need for continued research into the etiology of idiopathic prepubertal gynecomastia.

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