Determining the Importance of Lifestyle Risk Factors in Predicting Binge Eating Disorder After Bariatric Surgery...

Area of Science:

• Bariatric Surgery
• Psychology
• Public Health

Background:

• Lifestyle risk factors (LRF) are increasingly recognized as potential contributors to post-surgical outcomes.
• Binge eating disorder (BED) is a significant concern following bariatric procedures like laparoscopic sleeve gastrectomy (LSG).
• Understanding the interplay between LRF and BED post-LSG is vital for patient management.

Purpose of the Study:

• To assess the association between lifestyle risk factors (LRF) and the odds of developing binge eating disorder (BED) two years after laparoscopic sleeve gastrectomy (LSG).
• To evaluate the predictive capabilities of various machine learning (ML) models in identifying individuals at risk for BED post-LSG.
• To determine the impact of a cumulative lifestyle score (LS) on BED prevalence.

Main Methods:

• A cohort of 450 individuals who underwent LSG two years prior were analyzed.
• BED was assessed using the BES questionnaire; LRF data included smoking, alcohol, physical activity (PA), diet, BMI, and excess weight loss (EWL%).
• Machine learning models (logistic regression, KNN, decision tree, random forest, SVM, XGBoost, ANN) and a lifestyle score (LS) were employed.

Main Results:

• 26.1% of participants developed BED two years post-LSG.
• Individuals in the highest quartile of the lifestyle score (poorest lifestyle) had three times higher odds of BED (p=0.01).
• Random forest, logistic regression, SVM, and ANN models achieved approximately 75% accuracy in predicting BED. Insufficient PA, lower vegetable intake, higher BMI, and lower EWL% were independently associated with BED.

Conclusions:

• Poor lifestyle patterns are significantly associated with an increased likelihood of developing BED after LSG.
• The study highlights the importance of monitoring and addressing lifestyle risk factors in patients post-bariatric surgery.
• Targeted interventions focusing on lifestyle modifications may help mitigate BED development in this population.