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Genetic Landscape of Mucosal Melanoma: Identifying Pathogenic Germline Variants

Isabella Ribaudo1, Michelle Arbesman1, Ying Ni1

  • 1Cleveland Clinic, Cleveland, Ohio, USA.

Pigment Cell & Melanoma Research
|March 5, 2025
PubMed
Summary

Mucosal melanomas (MM) show a high prevalence of inherited cancer-predisposing genetic variants. Fifty percent of patients carried pathogenic germline variants, suggesting a germline-driven susceptibility in this rare cancer.

Keywords:
cancer susceptibilitygenetic predisposition to diseasegenetic testinggeneticsmelanomamucosal melanoma

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