[Morphological changes in the trunk and branches of the pulmonary artery in metastatic lung cancer]

Morphological changes in the lung artery and its branches were studied in 20 autopsy cases with carcinoma metastasis into the lung. Certain general lesions in the arteries, such as alteration and sclerosis of their walls due to intoxication and hypoxia as well as local changes in the form of allergic arteritis were detected. Immune genesis of the allergic arteritis is assumed, being a local allergic reaction to the tumour cells in the lumen of blood and lymph vessels. The importance of morphological changes in the lung vessels in the development of cardiopulmonary insufficiency in cases of various carcinomas with lung metastasis is demonstrated.