Related Experiment Video
Updated: May 24, 2025
13:45
Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
9.9K
Metastatic Merkel Cell Carcinoma
Andrew Krane1, Vijairam Selvaraj1, Andrew Hsu2
1Department of Medicine Warren Alpert Medical School at Brown University.
The Brown Journal of Hospital Medicine
|March 6, 2025
Abstract:
Merkel cell carcinoma is a rare, aggressive skin cancer that affects mainly the sun exposed areas in the elderly, especially the head and neck. Immunohistochemical analysis is necessary to establish diagnosis. We describe an elderly male who presented with hematochezia and was incidentally noted to have liver lesion on abdominal imaging, which was subsequently diagnosed as Merkel cell carcinoma.
Related Concept Videos
02:30Metastasis
5.5K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.5K
02:38Mitogens and the Cell Cycle
6.4K
Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
6.4K