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Local drug delivery for regeneration and disinfection in endodontics: A narrative review
Anu Elsa Swaroop1, Sylvia Mathew1, P Harshini1
1Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
Abstract:
Local Drug Delivery Systems (LDDSs) represent a significant development in endodontic therapy, offering targeted, effective treatment options for managing root canal infections and regenerative outcomes. LDDS can be customized to deliver antimicrobial agents and/or bioactive components to the specific site to address challenges associated with resistant microbial species and enhance regenerative outcomes. Further research in this area is essential to optimize these systems to improve clinical success. This article attempts to review the existing literature on the different LDDS in endodontics. Relevant scientific literature related to the topic was searched in PubMed, Google Scholar, and Scopus, critically analyzed and their data were extracted.
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