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Updated: May 24, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease
Luis E Ospina Velasquez1, Konstantinos A Papadakis1, Siri A Urquhart1
1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.
Abstract:
Immunoglobulin A vasculitis (IgAV) is an immune-mediated disorder that commonly involves dermatologic, musculoskeletal, renal, and gastrointestinal systems. Drug-induced cases of IgAV are rare and sparsely documented in the literature. We report a case of a patient with Crohn's disease who developed a tender, palpable purpuric rash on the torso and extremities 3 weeks after receiving a dose of ustekinumab. This case underscores the importance of considering IgAV in patients with inflammatory bowel disease who present with cutaneous symptoms while undergoing treatment with advanced therapies.
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