Emerging hybrid techniques in aortic valve interventions: A systematic review of integrating surgical and...

This systematic review examines the development and clinical application of hybrid aortic valve interventions that integrate surgical and transcatheter techniques. It focuses on the efficacy, outcomes, and innovations of these procedures, particularly for patients at moderate-to-high surgical risk.

A comprehensive database search (PubMed, Ovid, Web of Science, Cochrane, CINAHL, Embase, Scopus) was conducted from August 20 to October 10, 2024. Studies on aortic valve interventions combining surgical and transcatheter approaches were included, encompassing case studies, series, cohort studies, and reviews. Non-English articles, gray literature, cadaveric, and animal studies were excluded. Screening followed Preferred Reporting Items for Systematic Review and Meta-Analysis 2023 guidelines, with two rounds performed. Formal quality assessment was omitted due to study heterogeneity.

Out of 2046 initial articles, 495 unique studies remained after duplicate removal, and 65 articles were selected for analysis. Hybrid aortic valve procedures, blending surgical techniques with transcatheter aortic valve implantation, demonstrated improved outcomes, including shorter recovery times, reduced complications, and personalized treatment options for moderate-risk patients.

Hybrid aortic valve interventions mark a significant advancement, enhancing patient-specific care and outcomes. Continued innovation in materials, techniques, and clinician training is crucial to improve durability, long-term outcomes, and broader adoption of these minimally invasive procedures. Future research should address these areas to further optimize cardiovascular care.