Molecular Release by the Rotaxane and Pseudorotaxane Approach

The controlled release of target molecules is a relevant application in several areas, such as medicine, fragrance chemistry and catalysis. Systems which pursue this implementation require a fine-tune of the start and rate of the release, among other properties. In this scenario, rotaxane- and pseudorotaxane-based systems are postulated as ideal scaffolds to accomplish a precise cargo release, due to the special features provided by the intertwined arrangement. This short review covers advances towards the controlled release of different molecules using rotaxane- and pseudorotaxane-based systems, both in solution and in the solid state.