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Updated: May 24, 2025

Visualization and Quantification of Endogenous Intra-Organelle Protein Interactions at ER-Mitochondria Contact Sites by Proximity Ligation Assays
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Disease-Associated Factors at the Endoplasmic Reticulum-Golgi Interface.

Miharu Maeda1, Masashi Arakawa1, Kota Saito1

  • 1Department of Biological Informatics and Experimental Therapeutics, Graduate School of Medicine, Akita University, Akita, Japan.

Traffic (Copenhagen, Denmark)
|March 6, 2025
PubMed
Summary

The endoplasmic reticulum (ER)-Golgi interface is crucial for protein transport and recycling. Dysfunctional ER-Golgi transport factors are linked to various diseases, prompting a review of cellular effects and therapeutic strategies.

Keywords:
COPICOPIIER exit siteERGICGolgiTRAPP complexdisease‐associated factorendoplasmic reticulumliquid‐phase separationnonvesicular transport

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