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Related Concept Videos

Knee Joint01:23

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

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Synovial Fluid Analysis to Identify Osteoarthritis
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Psoriatic Arthritis - A Mortality Abstract.

De-Ann R Williams

    Journal of Insurance Medicine (New York, N.Y.)
    |March 6, 2025
    PubMed
    Summary

    Psoriatic arthritis patients show increased mortality risk starting year 4. This finding is crucial for life insurance underwriting, highlighting the need to consider disease severity and treatment in risk assessment.

    Area of Science:

    • Rheumatology
    • Actuarial Science
    • Life Insurance Underwriting

    Background:

    • Psoriatic arthritis (PsA) is a chronic inflammatory disease.
    • Accurate mortality statistics are essential for life insurance underwriting.
    • Previous studies may not fully capture long-term mortality risks in PsA.

    Purpose of the Study:

    • To analyze all-cause mortality in psoriatic arthritis patients compared to a matched population.
    • To derive mortality statistics applicable to life insurance underwriting.
    • To assess the impact of disease severity and treatment on mortality.

    Main Methods:

    • Utilized the pixel method to extract cumulative survival data from a published study.
    • Analyzed mortality data from psoriatic arthritis patients and comparator subjects.
    Keywords:
    Psoriatic arthritismortality

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  • Examined pharmacological treatment data to infer disease severity.

    • Main Results:

    • Mortality risk increased in psoriatic arthritis patients starting from year 4.
    • This aligns with established Table ratings for PsA.
    • Only 28% of patients received advanced therapies, suggesting a cohort with milder disease.

    Conclusions:

    • Comparative mortality findings support current Table ratings for psoriatic arthritis.
    • Understanding treatment profiles and disease severity is vital for accurate life insurance risk assessment.
    • The study emphasizes the need for nuanced underwriting considering individual patient factors.