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Engineering Approach to Study the Effect of TEVAR on the Cardiovascular System: A Systematic Review
Marco Magliocco1, Michele Conti2, Bianca Pane3
1Department of Experimental Medicine, University of Genoa, Genoa, Italy.
Annals of Vascular Surgery
|March 6, 2025
Summary
Thoracic Endovascular Aortic Repair (TEVAR) can alter cardiac geometry and improve blood flow dynamics. However, limited and varied studies highlight the need for standardized engineering analysis methods for clinical integration.
Area of Science:
- Cardiovascular Engineering
- Medical Imaging Analysis
- Computational Fluid Dynamics
Background:
- Investigating the impact of Thoracic Endovascular Aortic Repair (TEVAR) on cardiac geometry.
- Evaluating hemodynamic and cardiovascular biomechanical changes post-stent placement.
Purpose of the Study:
- To analyze the effects of TEVAR on left ventricular mass.
- To assess fluid dynamics parameters like Wall Shear Stress (WSS), flow, and velocity.
Main Methods:
- Systematic review of 11 studies using engineering methods (computational analysis, simulations).
- Analysis of 3D cardiovascular models derived from medical imaging.
- Quality assessment using the Newcastle-Ottawa scale.
Main Results:
- Increased left ventricular mass observed post-TEVAR.
- Improved flow conditions and reduced stress noted after aortic pathology exclusion.
- High discrepancy in methodologies and results across studies.
Conclusions:
- TEVAR induces changes in vascular structures.
- Current literature is limited, with varied methodologies and follow-up durations.
- Standardization of analysis methods is crucial for clinical integration of computational simulations.
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