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Updated: May 24, 2025

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
[Prophylactic surgery and genetic counselling: What impact of the artificial intelligence?]
1Département de médecine oncologique, Gustave-Roussy, 94805 Villejuif, France.
Abstract:
In the area of cancer predisposition, certain situations may lead to the discussion of prophylactic surgery. This is rarely strictly recommended and depends on the patient's choice. The advantages and disadvantages must be weighed up. The main advantage of prophylactic surgery is obviously risk reduction. At present, this risk is assessed on an individual basis using "classical" instruments. Artificial intelligence is expected to improve the selection of useful genetic information, the classification of variants of unknown significance, the combination of more comprehensive analysis results and the ability to associate them with non-genetic features. Artificial intelligence could also help to make genetic testing more accessible to people, or even contribute to direct patient information. This last point is likely to require considerable vigilance.
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