Related Experiment Video
Updated: May 24, 2025

Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice
Published on: January 13, 2012
Carotid Disease and Management
Khawaja Hassan Akhtar1, David C Metzger2, Faisal Latif3
1Department of Cardiovascular Diseases, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Abstract:
Carotid artery stenosis is a leading cause of stroke, and 25% of patients experience a recurrent stroke within 5 years. Early detection and treatment are important to reduce the risk of stroke. Optimal medical therapy should be ensured among these patients regardless of symptom status. Carotid artery revascularization with carotid endarterectomy or carotid artery stenting (CAS) should be considered among patients with symptomatic carotid stenosis, or among patients with severe asymptomatic carotid artery stenosis. Refined procedural techniques, improvement in stent design, and use of embolic protection devices have enhanced the efficacy of CAS while reducing the risk of procedural complications.
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