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Updated: May 6, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Renal and Mesenteric Artery Intervention
Jose D Tafur1, Khanjan B Shah2, Christopher J White3
1Department of Cardiovascular Diseases, John Ochsner Heart & Vascular Center, Ochsner Medical Center, The Ochsner Clinical School, Univ of Queensland, New Orleans, LA, USA.
Abstract:
Atherosclerotic disease of the abdominal aorta and its visceral branches poses significant health risks due to its potential to cause severe complications. Atherosclerosis affects renal and mesenteric vessels, contributing to renal artery stenosis and mesenteric ischemia, respectively, both of which can result in organ damage and ischemic bowel disease if left untreated. Therapy with guideline-directed medical therapy is advised in all patients. Chronic mesenteric ischemia (CMI) is infrequent and difficult to diagnose illness. Current evidence suggests that compared with open surgical repair, in anatomically suitable lesions, endovascular therapy is the most cost-effective choice for patients with CMI.
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