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Femoropopliteal Interventions for Peripheral Artery Disease: A Review of Current Evidence and Future Directions
Adam P Johnson1, Rajesh V Swaminathan2, Samantha D Minc3
1Department of Surgery, Division of Vascular and Endovascular Surgery, Duke University Health System, Durham, NC, USA; Durham Veterans Administration Medical Center, Durham, NC, USA.
Insights
Peripheral artery disease affecting the femoropopliteal segment can cause limb-threatening ischemia. This review summarizes current medical, endovascular, and surgical treatments for femoropopliteal artery occlusive disease.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Peripheral Artery Disease
Background:
- The femoropopliteal segment is a frequent site for peripheral artery disease (PAD).
- PAD in this region can manifest as claudication or critical limb ischemia, particularly with multilevel disease.
- Treatment options for femoropopliteal occlusive disease are diverse.
Purpose of the Study:
- To review current medical, endovascular, and surgical therapies for femoropopliteal artery occlusive disease.
- To summarize evolving management strategies based on patient factors and disease severity.
Main Methods:
- Literature review of current therapeutic options for femoropopliteal PAD.
- Synthesis of evidence regarding medical, exercise, endovascular, and open surgical interventions.
Main Results:
- Multiple treatment modalities exist for femoropopliteal artery occlusive disease.
- Management algorithms are evolving with advancements in endovascular and surgical techniques.
- Therapeutic goals vary based on patient presentation and disease extent.
Conclusions:
- Optimal management of femoropopliteal PAD requires consideration of patient-specific factors and disease characteristics.
- A comprehensive understanding of available therapies is crucial for effective treatment planning.
- Continued research is needed to refine best practices for femoropopliteal artery disease.
Abstract:
The femoropopliteal segment is a common anatomic location for peripheral artery disease. The clinical presentation of occlusive disease of the femoropopliteal segment can range from symptomatic or severe claudication if in isolation, or acute or chornic limb threatening ischemia often in the setting of multilevel disease. Patients can be treated with various therapies to improve symptoms and restore perfusion, including medical, exercise, endovascular, and open surgical therapies. The current literature is rapidly evolving on the best management algorithms and strategies based on patient presentation, severity of occlusive disease, and desired therapy goals. This paper summarizes current literature on available medical, endovascular, and surgical therapies for treating peripheral artery occlusive disease of the femoropopliteal segment.
