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[Ultrastructure of calcium-induced myocardial necrosis]
Insights
This study details ultrastructural changes in heart muscle cells during calcium-induced necrosis, identifying three distinct lesion types from reversible to irreversible stages.
Area of Science:
- Cardiovascular pathology
- Cellular biology
- Myocardial research
Abstract:
The authors present for the first time a complete picture of ultrastructural changes of contractile cardiomyocytes in myocardial calcium necroses in the time course from reversible to irreversible stages. Three types of calcium cell lesions are singled out: rigor, lytic, and vacuolar.