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Non-pharmaceutical interventions (NPIs) to control influenza spread among children in primary school and
Hui Xiang1, Jie Zhang2, Linlin Yang1
1Nanan District Center for Disease Control and Prevention, Chongqing, Nanan, China.
Insights
Symptom-based isolation and class-suspension effectively control influenza spread in young students. Symptom-based isolation proved more effective than class-suspension in primary schools, highlighting the need for health education and surveillance.
Area of Science:
- Public Health
- Epidemiology
- Pediatrics
Background:
- Non-pharmaceutical interventions (NPIs) are crucial for influenza control.
- Limited data exists on NPI effectiveness in pre-middle school students.
- This study addresses the need for evidence-based influenza control strategies in young children.
Purpose of the Study:
- To evaluate the effectiveness of class-suspension versus symptom-based isolation for controlling influenza spread.
- To provide data supporting NPI strategies for primary school and kindergarten settings.
- To inform public health policies for influenza prevention in children.
Main Methods:
- Two regions in Southwest China implemented class-suspension and symptom-based isolation.
- Outcome indicators included the effective reproduction number (RT), incidence cases, and attack rate.
- Statistical analysis was performed using R4.1.2 software with a significance level of p < 0.05.
Main Results:
- Both interventions significantly reduced RT values.
- Symptom-based isolation had fewer incident cases compared to class-suspension.
- A significant difference in attack rate was observed between the two interventions in primary schools.
Conclusions:
- Both symptom-based isolation and class-suspension are effective NPIs for influenza control.
- Symptom-based isolation demonstrated greater effectiveness than class-suspension in primary school settings.
- Continued health education and daily surveillance are recommended for influenza prevention in children.
Background:
Non-pharmaceutical interventions (NPIs) are critical for influenza control and prevention, however, the data about such interventions are insufficient among students in grades below middle school. Hence, this study aims to explore the effectiveness of NPIs (class-suspension and symptom-based isolation) on the control of influenza spread among children in primary school and kindergarten. Findings will support evidence-based strategies for influenza control among children enrolled in primary schools and kindergartens.
Methods:
We purposively selected two regions (Zigong and Nanan) in Southwest China as study places, and class-suspension and symptom-based isolation was conducted in the two regions, respectively. RT (effective reproduction number) value, incidence cases, and attack rate were considered as outcome indicators. R4.1.2 software was used to conduct statistical analysis, and p < 0.05 (two-tailed) was considered as statistically significant.
Results:
In total, 593 students in the Nanan district received symptom-based isolation while 1340 students in Zigong city received class-suspension. The vaccination rate of Zigong (21.27%) was much greater than Nanan (8.26%) (p < 0.001). Parents in the Nanan were more highly educated, with undergraduate, master and above degrees, compared to parents in the Zigong (p < 0.05). Though there was no statistical significance difference in RT between Nanan (1.23) and Zigong (1.16) after quarantine and control measures were conducted, the RT value in the two regions was sharply decreased. The incident cases after class-suspension was much higher than symptom-based isolation in both kindergarten and primary school. The attack rate had a significant difference between class-suspension and symptom-based isolation in primary school (p < 0.05).
Conclusions:
Both symptom-based isolation and class-suspension are effective measures in control of influenza spread, and symptom-based isolation are more effective than class-suspension in primary school. Health education and daily surveillance are needed in the control and prevention of influenza.
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