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Melanonychia induced by topical 5-fluorouracil
The British Journal of Dermatology
|May 1, 1985
Summary
Topical 5-fluorouracil treatment for warts caused nail pigmentation. This melanonychia, affecting all fingernails, mimicked effects seen with systemic cytotoxic drugs.
Area of Science:
- Dermatology
- Oncology
- Pharmacology
Background:
- Nail pigmentation (melanonychia) can be a side effect of certain medications.
- Periungual warts are benign skin growths often treated with topical agents.
- 5-fluorouracil is a chemotherapy agent with known side effects.