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Updated: Jul 25, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
Wessex perinatal mortality survey 1982.
Perinatal mortality in Wessex was 10.1/1000 births, with malformations and pregnancy/labor complications as key factors. Improved antenatal supervision and neonatal care are crucial for reducing infant deaths.
Area of Science:
- Perinatal Medicine
- Neonatalogy
- Public Health
Background:
- Perinatal mortality remains a significant concern in developed regions.
- Understanding the causes of perinatal death is essential for targeted interventions.
Purpose of the Study:
- To analyze the causes and contributing factors of perinatal deaths in the Wessex region.
- To identify areas for improvement in antenatal supervision and neonatal care.
Main Methods:
- Retrospective survey of 335 perinatal deaths in the Wessex region.
- Classification of deaths by malformations, timing (antenatal, intrapartum, postpartum), and infant weight.
- Analysis of maternal pregnancy complications and predisposing factors.
Main Results:
- Perinatal mortality rate was 10.1 per 1000 births.
- Lethal malformations caused 24% of deaths; 49% of normally formed infants died antenatally, 13% intrapartum.
- Over 60% of stillbirths exceeded 1500g; postpartum deaths often linked to labor complications and hypoxia.
- Maternal complications affected 50% of mothers; 185 neonatal deaths occurred, with congenital abnormalities in 46% of late neonatal deaths.
Conclusions:
- Significant proportions of perinatal deaths are attributable to malformations and complications of pregnancy and labor.
- Enhanced antenatal supervision, fetal distress monitoring, and improved early neonatal care are vital for reducing perinatal mortality.
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