Related Experiment Video
Updated: May 23, 2025

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
Effectiveness of the Nasal Irrigation Effectiveness in Treating Allergic Rhinitis in Children 6 to 12 Years Old
Bita Yadegari1, Hamidreza Houshmand2, Mir Reza Ghaemi3
1Department of Pediatrics, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran. Yadegari.b@gmail.com.
Insights
Nasal irrigation using saline solution significantly reduced sneezing and ocular symptoms in children with allergic rhinitis. This adjunct treatment improved their quality of life over three months.
Area of Science:
- Pediatric Allergy and Immunology
- Otolaryngology
Background:
- Nasal irrigation is a non-pharmacological method for nasal symptom relief.
- Caregiver acceptance is limited by procedural ambiguity and lack of standardized protocols.
Purpose of the Study:
- To evaluate the efficacy of normal saline nasal irrigation in children aged 6-12 with allergic rhinitis.
- To assess the impact on symptom severity and quality of life.
Main Methods:
- Prospective, randomized, single-blind trial.
- Children received standard care or standard care plus saline nasal irrigation (0.65% solution, 4 times daily).
- Symptom severity and quality of life were assessed using the Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ) at baseline, 1, and 3 months.
Main Results:
- The intervention group showed statistically significant reductions in sneezing frequency and need for nasal cleansing.
- Ocular symptoms (irritation, itching, watering) were significantly lower in the intervention group.
- While overall PRQLQ scores did not differ significantly, the intervention group showed a trend towards lower scores at 1 and 3 months.
Conclusions:
- Nasal irrigation with 0.65% saline solution 4 times daily may be an effective adjunct treatment for pediatric allergic rhinitis.
- This regimen can significantly improve nasal symptom severity and enhance quality of life in children.
- Further standardization of protocols could increase caregiver acceptance and adoption.
Abstract:
Nasal irrigation, a nonpharmacological intervention for alleviating nasal symptoms, has yet to gain widespread acceptance among caregivers due to procedural ambiguities and the absence of a standardized protocol. This study aimed to evaluate the efficacy of normal saline nasal irrigation in managing allergic rhinitis among children aged 6 to 12 years. This prospective, randomized, single-blind trial enrolled children aged 6 to 12 with allergic rhinitis. Patients were randomly assigned to receive either standard care (oral antihistamine and intranasal corticosteroid) or standard care plus nasal irrigation with saline solution. Symptom severity, assessed using the Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ) at baseline, 1, and 3 months, included rhinorrhea, nasal congestion, sneezing, pruritus, ocular symptoms, and functional impairment. The intervention group demonstrated statistically significant improvements in several domains post-intervention. Specifically, a marked reduction in sneezing frequency and nasal cleansing requirements was observed. Moreover, this group reported significantly lower ocular symptoms, including irritation, itching, and watering, relative to the control group. Although overall PRQLQ scores did not differ significantly between groups, the intervention group exhibited lower scores at the 1- and 3-month follow-ups, indicative of enhanced quality of life. These findings suggest a potential beneficial effect of the intervention on participant well-being. The findings of this study indicate that nasal irrigation with 0.65% saline solution 4 times daily may serve as an effective adjunct treatment for children with allergic rhinitis. This regimen was associated with significant enhancements in both nasal symptom severity and quality of life.
Related Concept Videos
Suctioning the Nasopharyngeal Airway
Equipment Required
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Tonsillitis II: Management
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

