Multiple comparisons in the randomization analysis of designed experiments with growth curve responses
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Updated: Oct 27, 2026

Precise, High-throughput Analysis of Bacterial Growth
Published on: September 19, 2017
Abstract:
A randomization approach to multiple comparisons is developed for comparing several growth curves in randomized experiments. The exact Type I probability error rate for these comparisons may be prespecified, and a Type I error probability for each component test can be evaluated. These procedures are free of many of the standard assumptions for analyzing growth curves and for making multiple comparisons. An application of the procedure gives all pairwise comparisons among the mean growth curves associated with four treatments in an animal experiment using a Youden square design, where growth curves are obtained on monitoring hormone levels over time.
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