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Updated: Jun 16, 2025
07:49
Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
Published on: July 17, 2019
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Long-term outcomes with single-agent BRAF inhibitor therapy in Erdheim-Chester disease
Gaurav Goyal1, Anne S Reiner2, Dana Bossert3
1Division of Hematology and Oncology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL.
Blood
|March 7, 2025
Abstract:
Among 64 patients with Erdheim-Chester disease treated with a BRAF inhibitor (median follow-up 4 years), we found high response rates (85%) but frequent discontinuations (61%), primarily because of adverse events. Additionally, patients experienced poor health-related quality of life and high symptom burden.
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