Voluntary multifetal pregnancy reduction: who should decide and select, and why?
Sara Patuzzo Manzati1, Chiara Casprini2, Mariachiara Bosco2
1Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, Piazza A. Stefani 1, 37125 Verona, Italy.
Summary
Multifetal Pregnancy Reduction (MPR) has increased due to assisted reproduction, leading to ethical questions. This review examines MPR
Area of Science:
- Reproductive Medicine
- Bioethics
- Medical Law
Background:
- Assisted reproductive technologies have significantly increased the incidence of multiple pregnancies over the past four decades.
- Multiple pregnancies are associated with higher risks of complications, including fetal loss and preterm birth.
- Multifetal Pregnancy Reduction (MPR) has emerged as an intervention to mitigate these risks.
Purpose of the Study:
- To explore the ethical dilemmas associated with Multifetal Pregnancy Reduction.
- To review various clinical scenarios and legal frameworks relevant to MPR.
- To foster a bioethical discussion to guide clinical practice in MPR.
Main Methods:
- Review of existing literature on assisted reproduction and multiple pregnancies.
- Analysis of ethical considerations in selective reduction of fetuses.
- Examination of legal precedents and regulations concerning elective abortion and pregnancy interventions.
Main Results:
- The rise in assisted reproduction necessitates a thorough ethical and legal evaluation of MPR.
- MPR presents complex ethical challenges requiring careful consideration of patient autonomy, fetal status, and medical indications.
- Existing laws on elective abortion may require reinterpretation or adaptation to address the nuances of MPR.
Conclusions:
- A comprehensive bioethical framework is essential for navigating the complexities of MPR.
- Clinical practice guidelines should be informed by ethical deliberation and legal understanding.
- Further discourse is needed to address the evolving landscape of reproductive medicine and its implications.


