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Updated: May 6, 2026

Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells
Published on: August 16, 2018
Stripe out for brain evolution: Astrocytes go human
Lara López-González1, Víctor Borrell1
1Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas & Universidad Miguel Hernández, Sant Joan d'Alacant 03550, Spain.
Abstract:
Evolution of the human brain involved neuron and glial cell changes. In this issue of Cell Stem Cell, Ciuba et al.1 identify an epigenetic mechanism central in the evolution of human astrocytes, where small enhancer modifications increased transcription factor binding, orchestrating transcriptomic changes that influence astrocyte structure and function.
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