Giant Coronary Pseudoaneurysm Due to Behçet's Disease

Zafer Sattouf1, Bilal Ali1, Sanjana Datla1

  • 1Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

JACC. Case Reports
|March 7, 2025
PubMed

Insights

Behçet's disease, a rare systemic vasculitis, can cause giant coronary artery pseudoaneurysms. This case highlights a young man with Behçet's disease presenting with acute coronary syndrome due to this rare cardiac complication.

Area of Science:

  • Cardiology
  • Rheumatology
  • Systemic Vasculitis

Background:

  • Behçet's disease (BD) is a systemic vasculitis with diverse clinical features.
  • Cardiovascular involvement, though rare, can be severe in BD.
  • Coronary artery pseudoaneurysms are an exceptionally uncommon complication of BD.

Observation:

  • A 27-year-old male with a history of Behçet's disease presented with acute coronary syndrome.
  • Diagnostic imaging revealed a giant saccular coronary pseudoaneurysm as the cause of his symptoms.

Findings:

  • The patient's acute coronary syndrome was attributed to a giant coronary artery pseudoaneurysm.
  • This represents a rare but serious cardiovascular manifestation of Behçet's disease.

Implications:

  • Early recognition and management of coronary pseudoaneurysms in BD patients are crucial.
  • Immunosuppressive therapy combined with surgical intervention like coronary artery bypass grafting offers good outcomes for suitable candidates.
  • This case underscores the importance of considering rare cardiovascular complications in the management of Behçet's disease.