Giant Coronary Pseudoaneurysm Due to Behçet's Disease
Related Experiment Video
Updated: May 23, 2025

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
Published on: September 8, 2023
Zafer Sattouf1, Bilal Ali1, Sanjana Datla1
1Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Insights
Behçet's disease, a rare systemic vasculitis, can cause giant coronary artery pseudoaneurysms. This case highlights a young man with Behçet's disease presenting with acute coronary syndrome due to this rare cardiac complication.
Area of Science:
- Cardiology
- Rheumatology
- Systemic Vasculitis
Background:
- Behçet's disease (BD) is a systemic vasculitis with diverse clinical features.
- Cardiovascular involvement, though rare, can be severe in BD.
- Coronary artery pseudoaneurysms are an exceptionally uncommon complication of BD.
Observation:
- A 27-year-old male with a history of Behçet's disease presented with acute coronary syndrome.
- Diagnostic imaging revealed a giant saccular coronary pseudoaneurysm as the cause of his symptoms.
Findings:
- The patient's acute coronary syndrome was attributed to a giant coronary artery pseudoaneurysm.
- This represents a rare but serious cardiovascular manifestation of Behçet's disease.
Implications:
- Early recognition and management of coronary pseudoaneurysms in BD patients are crucial.
- Immunosuppressive therapy combined with surgical intervention like coronary artery bypass grafting offers good outcomes for suitable candidates.
- This case underscores the importance of considering rare cardiovascular complications in the management of Behçet's disease.
Abstract:
Behçet's disease (BD) is a systemic vasculitis which manifests through diverse clinical manifestations, including oral and genital ulcers, and ocular lesions, and has potential for neurologic, gastrointestinal, and cardiovascular involvement. Coronary artery pseudoaneurysm is a very rare complication of BD. This paper presents the case of a giant coronary pseudoaneurysm presenting with acute coronary syndrome. Immunosuppressive therapy and coronary artery bypass grafting remain the most common treatment approach and are associated with excellent outcomes in surgically suitable candidates. This paper presents a case of a 27-year-old man with a history of BD presenting with acute coronary syndrome due to giant saccular coronary pseudoaneurysm.
Related Concept Videos
Esophageal Varices-I: Introduction
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...

