Adult Hydrocephalus: Natural History, Clinical Outcomes, Quality of Life, and Health Economics

Adult hydrocephalus comprise a family of disorders characterized by a cerebrospinal fluid dynamic disturbance and a shared core symptomatology. Idiopathic normal pressure hydrocephalus (iNPH) has gained an increasing scientific attention over the past decades and is the most studied type of adult hydrocephalus. While knowledge of iNPH have accumulated and expanded, literature is still meagre in other, more uncommon adult hydrocephalus. In this focused review, we describe the most important advances in the literature on natural course, outcomes, quality of life and health economics with a focus on iNPH, the type of adult hydrocephalus where substantial research data exist.