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Biometry combining Scheimpflug imaging and partial coherence interferometry versus standard partial coherence

V E W C M van Renterghem1, F-X Crahay1

  • 1Centre Hospitalier Régionale Citadelle, Liège, Belgium.

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|March 8, 2025
PubMed
Summary
This summary is machine-generated.

The Pentacam® AXL and IOL Master 500 biometers show significant differences in keratometry and axial length measurements. These differences mean the devices cannot be used interchangeably for eye measurements.

Keywords:
Anterior chamber depthAstigmatismAstigmatismeAxial lengthIOL Master 500Longueur axialePentacam® AXLProfondeur de la chambre antérieure

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optometry

Background:

  • Accurate biometric measurements are crucial for refractive surgery outcomes.
  • Several devices are available for measuring ocular parameters, but inter-device variability can impact clinical decisions.

Purpose of the Study:

  • To compare measurements of mean keratometry (K), axial length (AL), astigmatism vectors (J0 and J45), astigmatism magnitude, white-to-white (WTW) diameter, and anterior chamber depth (ACD) between the Pentacam® AXL and IOL Master 500 biometers.

Main Methods:

  • A retrospective reliability analysis was conducted on 328 eyes of 187 patients undergoing cataract or refractive lens exchange surgery.
  • Ocular parameters were measured preoperatively using both the Pentacam® AXL (Scheimpflug imaging and partial coherence interferometry) and the IOL Master 500 (optical biometry).

Main Results:

  • Significant differences (P<0.05) were found in mean keratometry, axial length, ACD, WTW diameter, and astigmatism magnitude between the two devices.
  • Pentacam® AXL yielded flatter keratometry and greater axial length measurements compared to the IOL Master 500, though the axial length difference was not clinically significant.
  • Measurements of J0 and J45 astigmatism vectors did not significantly differ between the devices.

Conclusions:

  • The Pentacam® AXL and IOL Master 500 exhibit statistically significant differences in several key biometric measurements.
  • These discrepancies indicate that the Pentacam® AXL and IOL Master 500 are not interchangeable for clinical use in preoperative planning.