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Updated: Jul 2, 2026

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Analyzing outcomes of platelet-rich plasma usage on surgical wounds: A systematic review

Malihe Ranjbar Moghaddam1, Amirmohammad Merajikhah2, Bahareh Mahdood3

  • 1School of Nursing and Midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.

Current Problems in Surgery
|March 8, 2025
PubMed
Abstract

No abstract available in PubMed .

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Formation of the Platelet Plug01:22

Formation of the Platelet Plug

The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...