Related Experiment Video
Updated: May 23, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Prevalence and associated factors of immunization among under-five children in Somalia
Denekew Bitew Belay1,2, Mahad Ibrahim Ali3, Ding-Geng Chen4,5
1Department of Statistics, Bahir Dar University, Bahir Dar, Ethiopia. denekew.t.h@gmail.com.
Background:
Children worldwide can live lives free from various illnesses and disabilities due to vaccination. For instance, vaccination has eliminated smallpox, a deformative and frequently fatal illness that claimed an estimated 300 million lives in the twentieth century. However, due to a lack of access to immunization and other health services, 14.3 million infants in 2022 still did not receive their first dose of the Diphtheria-Tetanus-Pertussis (DTP) vaccine, and an additional 6.2 million received only a portion of the scheduled dose. This study aimed to assess prevalence and determinant factors of immunization among under-five children in Somalia using Somalia Health and Demographic Survey (SHDS) Data.
Methods:
The study design was cross-sectional, utilizing the SHDS 2020 data. A total of 3916 under-five children who fulfilled the inclusion criteria were included in this study. Count regression models were employed to explore factors associated with the number of vaccinations received per child.
Results:
In this study, 9.14% of children did not receive any vaccination during their childhood. Different candidate count regression models were compared. Using AIC and BIC, the Negative-binomial (NB) regression model was found to be the best fit. From this model, we found that women ages 20-24 (IRR = 1.192, 95% CI: 1.083, 1.313) and 25-29 (IRR = 1.180, 95% CI: 1.068, 1.305) had a higher number of vaccinations per child compared to women in the 15-19 age group. Women who attended primary education (IRR = 1.090, 95% CI: 1.034, 1.150) and secondary education (IRR = 1.157, 95% CI: 1.058, 1.266) had a higher number of vaccinations per child compared to uneducated women) also correlated with increased vaccination Parity (IRR = 1.090, 95% CI: 1.031-1.153), and wealth quantile (IRR = 1.110, 95% CI: 1.012, 1.217) positively influenced vaccination attendance. Regional disparities were also found to be significant, with Togdheer, Sool, Sanaag, Bari, Nugaal, Bay, Bakool, Mudug, Hiiraan and Galgaduud significantly different from Awdal region. In Negative-Binomial, age, region, residence, educational level, wealth quantile, child size at birth, parity and birth order emerged as key predictors, revealing complex determinants of vaccination utilization in Somalia.
Conclusions:
A large proportion of children did not complete the full vaccination schedule. Socio-demographic factors, such as age, region, residence, educational level, wealth quantile, child size at birth, parity, and birth order, had a significant impact on the number of children vaccinated in Somalia. These findings underscore the importance of targeted interventions for addressing these factors. Implementing initiatives based on these conclusions has the potential to enhance vaccination coverage and child health outcomes.
More Related Videos
08:12Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
09:57Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay
Published on: August 6, 2020
Related Concept Videos
Vaccinations
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Principles of Disease Surveillance
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...