[Diagnostic approach and management of left intraventricular thrombus complicated by unexpected embolism : A case

Thibaut Renotte1, Théophile Tamakloe2, Jean-Louis Mariage3

  • 1Médecine Interne, UCLouvain - Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Bruxelles, Belgique.

Annales De Cardiologie Et D'Angeiologie
|March 9, 2025
PubMed

Insights

Left ventricular thrombus (LVT), a complication of heart conditions, can lead to dangerous embolisms. This case shows LVT causing splenic infarction years later, emphasizing advanced imaging and new anticoagulant therapies.

Area of Science:

  • Cardiology
  • Vascular Medicine

Background:

  • Left ventricular thrombus (LVT) is a significant complication in ischemic and non-ischemic cardiomyopathies.
  • Systemic embolism from LVT poses a high risk of morbidity and mortality.

Purpose of the Study:

  • To present a case of LVT leading to splenic infarction and abscessed hematoma.
  • To highlight the diagnostic role of advanced medical imaging for LVT.
  • To discuss the therapeutic potential of direct oral anticoagulants in managing LVT.

Main Methods:

  • Case report of a 73-year-old male with a history of myocardial infarction.
  • Utilized advanced medical imaging for diagnosis.
  • Reviewed current evidence on LVT management.

Main Results:

  • An apical LVT, present for seven years post-myocardial infarction, caused splenic infarction and an abscessed hematoma.
  • Advanced imaging was crucial for diagnosing the LVT and its complications.
  • Direct oral anticoagulants show emerging therapeutic promise.

Conclusions:

  • This case underscores the delayed complications of LVT and the importance of vigilant monitoring.
  • Advanced imaging is critical for accurate LVT diagnosis.
  • Optimizing LVT management requires ongoing review of therapeutic strategies, including novel anticoagulants.