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Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
[Drug-induced liver injury due to asymptomatically discovered Saire-to: a case report]
Soshi Oyama1, Kazuo Okumoto1, Shotaro Akiba1
1Department of Gastroenterology, Yamagata Prefectural Shinjo Hospital.
Abstract:
A 59-year-old female patient was prescribed Saire-to for dizziness. She demonstrated no symptoms, but a blood test conducted after 5 months revealed liver dysfunction, and thus she was referred to and admitted to our hospital. Her condition rapidly improved after drug discontinuation, and a liver biopsy test confirmed drug-induced liver injury, with a positive drug-induced lymphocyte stimulation test. Herbal medicine-induced liver damage has been increasing in recent years, many of which contain Ougon. Herbal medicines that contain Ougon pose a risk of liver damage;thus, regular blood tests are required even in the absence of symptoms.
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