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Current Issues of Next-Generation Sequencing-Based Circulating Tumor DNA Analysis in Colorectal Cancer

Narmadha Rathnasamy1, Viraj Lavingia2, Shyam Aggarwal3

  • 1Department of Medical Oncology, Royal Care Superspeciality Hospital, Coimbatore, Tamil Nadu, India.

South Asian Journal of Cancer
|March 10, 2025
PubMed

Keywords:
molecularmonitoringprogressionresidual diseasetargeted

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.