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Updated: May 23, 2025

Integrated Compensatory Responses in a Human Model of Hemorrhage
Published on: November 20, 2016
Management of gastrointestinal bleed in the intensive care setting, an updated literature review
Vignesh K Nagesh1, Sai Priyanka Pulipaka2, Ruchi Bhuju2
1Department of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States. vgneshkrishnan@gmail.com.
Abstract:
Gastrointestinal (GI) bleeding is a critical and potentially life-threatening condition frequently observed in the intensive care unit (ICU). This literature review consolidates current insights on the epidemiology, etiology, management, and outcomes of GI bleeding in critically ill patients. GI bleeding remains a significant concern, especially among patients with underlying risk factors such as coagulopathy, mechanical ventilation, and renal failure. Managing GI bleeding in the ICU requires a multidisciplinary approach, including resuscitation, endoscopic intervention, pharmacologic therapy, and sometimes surgical procedures. Even with enhanced management strategies, GI bleeding in the ICU is associated with considerable morbidity and mortality, particularly when complicated by multi-organ failure. This review reiterates the need for adequate resuscitation and interventions in managing GI bleeding in critically ill patients, aiming to enhance survival rates and improve the quality of care within the ICU setting.
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