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Updated: May 23, 2025

Hybrid µCT-FMT imaging and image analysis
Published on: June 4, 2015
Improving osteoarticular characterization in magnetic resonance imaging: the role of simulated computed tomography
Gabriel Brito-Barbosa1, Felipe Bortoloni Pires Correa1, Leonor Garbin Savarese1
1Department of Medical Imaging, Hematology, and Clinical Oncology, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil.
Abstract:
Increasing tissue contrast for bone assessment on magnetic resonance imaging has been the aim of several recent studies, and various techniques have been proposed for that purpose, including ultrashort echo time sequences, zero echo time sequences, and gradient echo sequences in various acquisition forms. In this article, we discuss the fast field echo resembling a computed tomography using restricted echo-spacing (FRACTURE) sequence, which we have started to use routinely in our practice. The FRACTURE sequences are based on the acquisition of gradient echo sequences with different echo times and specific postprocessing. Gradient echo sequences are widely available on magnetic resonance imaging scanners, which is an advantage for the use of a FRACTURE sequence. However, being more susceptible to metal artifacts, a FRACTURE sequence is of limited utility in patients with metallic implants or medical devices. The aim of this article is to illustrate the use of FRACTURE sequences in various contexts, including osteoarticular infection, inflammatory arthropathy, bone tumors, fractures, and crystal deposition diseases.
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