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Lateral Transorbital Approach for Lateral Sphenoid Defects: Anatomy, Surgery, Nasoseptal Flap Use, and a 4-Case
Darlene Lubbe1, Lien Deschuytere1, Kris S Moe2
1Division of Otorhinolaryngology University of Cape Town Cape Town South Africa.
Laryngoscope Investigative Otolaryngology
|March 10, 2025
Summary
The lateral transorbital approach offers effective skull base repair for pneumatized sphenoid sinus defects, reducing nasal complications. This technique, along with nasoseptal flaps, provides a valuable alternative for cerebrospinal fluid (CSF) leak repair.
Area of Science:
- Otorhinolaryngology
- Neurosurgery
- Skull Base Surgery
Background:
- Complex skull base repairs, particularly in the lateral recess of pneumatized sphenoid sinuses, present surgical challenges.
- Standard transnasal methods may lead to nasal morbidity and hypesthesia.
Purpose of the Study:
- To evaluate the effectiveness and anatomical benefits of the lateral transorbital approach for complex skull base repairs.
- To compare this approach with traditional transnasal techniques.
Main Methods:
- A case series involving four patients from two institutions was conducted.
- Three patients with spontaneous cerebrospinal fluid (CSF) leaks underwent lateral transorbital repair; one with skull base fractures received a combined transnasal and transorbital repair using a nasoseptal flap.
Main Results:
- The lateral transorbital approach provided effective access to the lateral sphenoid recess using standard instruments.
- This method avoided nasal morbidity and hypesthesia associated with transpterygoid access.
- Nasoseptal flaps, when needed, were placed under direct vision via the transorbital route for complex defects.
Conclusions:
- The lateral transorbital approach improves visualization and reduces nerve injury risk for pneumatized sphenoid sinus defect repair.
- It offers a valuable alternative with lower nasal morbidity.
- The nasoseptal flap is effective for cerebrospinal fluid (CSF) leak prevention in transorbital procedures.

