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Comparative Evaluation of Efficacy of Povidone-Iodine on Covid-19 Viral Load - A Systematic Review and Meta-Analysis
Sriram C Mallick1, S Bhuvaneshwari1, N C Sangamesh1
1Department of Oral Medicine Diagnosis and Radiology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.
Introduction:
To assess if povidone-iodine is a more effective mouthwash than other mouthwashes in treating COVID-19.
Materials And Methods:
The review was completed in compliance with PRISMA principles and entered into PROSPERO. Databases on electronic devices were examined. Using RevMan software version 5.3, the Cochrane risk of bias (ROB) -2 tool was employed for quality evaluation.
Results:
When compared to other mouthwashes, povidone-iodine was shown to reduce the COVID-19 viral load on average by 0.11 (-0.67-0.44) times, however, this difference is not statistically significant.
Conclusion:
Povidone-iodine was found to have a substantial impact on lowering the COVID-19 viral load in COVID-19 patients when compared to the control group. Povidone-iodine appears to be safer for long-term use, although both mouthwashes were equally effective.
