Eggshell Derived Nanohydroxyapatite as a Bone Graft for Intrabony Defects was Evaluated Using (CBCT) - A Randomized...

Area of Science:

• Biomaterials Science
• Periodontology
• Regenerative Medicine

Background:

• Intrabony defects pose challenges in periodontal regeneration.
• Novel bone graft materials are needed to improve treatment outcomes.

Purpose of the Study:

• To evaluate the efficacy of eggshell-derived nanohydroxyapatite (EnHA) as a bone graft material.
• To assess EnHA's effectiveness in treating intrabony defects using clinical and cone-beam computed tomography (CBCT) parameters.

Main Methods:

• A 6-month study involving ten patients with intrabony defects, divided into 2-wall and 3-wall defect groups.
• Clinical assessments included clinical attachment level (CAL), probing depth (PD), and gingival recession (GR).
• CBCT scans were performed pre-operatively and at multiple follow-up intervals (1, 3, and 5 months).

Main Results:

• Both groups showed significant reductions in CAL and PD.
• CBCT measurements indicated positive trends in bone regeneration.
• The 3-wall defect group demonstrated notable improvements in periodontal health.

Conclusions:

• EnHA shows potential as a bone graft substitute for intrabony defects.
• Favorable clinical and CBCT outcomes support EnHA's efficacy over a 6-month period.