Related Experiment Video
Updated: May 23, 2025

Precision of In Vivo Quantitative Tooth Wear Measurement Using Intra-Oral Scans
Published on: July 12, 2022
Digit Ratio as Predictors of Dental Caries: A Study of the 2D:4D Relationship
M Ishwarya1, Vasanthakumari Ananthan1, Selvabalaji Arumugam1
1Department of Pediatric and Preventive Dentistry, Adhiparasakthi Dental College and Hospital, The Tamil Nadu Dr.M.G.R Medical University, Melmaruvathur, Tamil Nadu, India.
Aim:
This cross-sectional study aimed to investigate the association between caries risk and the 2D:4D ratio, a potential marker of prenatal hormone exposure, among children aged 5-12 years.
Methods:
A total of 250 children were examined. Caries indices decayed, missing and filled teeth/decayed, extracted and filled teeth (DMFT/deft) were recorded, and 2D:4D ratios were measured using a vernier caliper. Chi-square statistical analysis was conducted to explore the relationship between 2D:4D ratios and caries risk.
Results:
The study revealed a higher prevalence of caries among children with a low 2D:4D ratio (<1), suggesting elevated prenatal androgen levels. Specifically, 123 out of 147 individuals (83.67%) with a 2D:4D ratio less than 1 presented a high caries index, compared to 32 out of 103 individuals (31.07%) with a ratio equal to or greater than 1. Gender-specific differences were observed, with males exhibiting lower mean 2D:4D ratios than females.
Conclusion:
These findings suggest a potential role for the 2D:4D ratio as a predictive marker for dental caries risk in children.
Related Concept Videos
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...

