A Protocol for Body MRI/CT and Extraction of Imaging-Derived Phenotypes (IDPs) from the China Phenobank Project

Currently, standard protocols for body imaging and corresponding image processing pipelines in population-based cohort studies are unavailable, limiting the applications of body imaging. Based on the China Phenobank Project (CHPP), the present study described a body imaging protocol for multiple organs, including cardiac structures, liver, spleen, pancreas, kidneys, lung, prostate, and uterus, and the corresponding image processing pipelines promoted its development. Briefly, the body imaging protocol comprised a 40-min cardiac magnetic resonance imaging (MRI) scan, a 5-min computed tomography (CT) scan, a 20-min abdominal MRI scan, and a 10-min pelvic MRI scan. The recommended image processing pipeline utilized deep learning segmentation models to facilitate the analysis of large amount of data. This study aimed to provide a reference for planning studies based on the CHPP platform.