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Central Dentinogenic Ghost Cell Tumor: A Rare Entity
Mary Nashashibi1, Amir Farah2, Imad Abu El-Naaj3
1Pathology, Tzafon Medical Center, Azrieli Faculty of Medicine, Bar Ilan University, Tiberias, ISR.
Abstract:
Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.3 cm expansile mass in the right mandibular body. The patient underwent radiographic and histologic assessment followed by tumor enucleation under local anesthesia, which revealed classic features of the DGCT, including ghost cells, calcifications, and a low proliferation index, consistent with low malignant potential.

