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Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.

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Related Experiment Video

Updated: May 13, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
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Central Dentinogenic Ghost Cell Tumor: A Rare Entity.

Mary Nashashibi1, Amir Farah2, Imad Abu El-Naaj3

  • 1Pathology, Tzafon Medical Center, Azrieli Faculty of Medicine, Bar Ilan University, Tiberias, ISR.

Cureus
|March 10, 2025
PubMed
Summary
This summary is machine-generated.

A rare dentinogenic ghost cell tumor (DGCT) presented as a painless mandibular mass in a 66-year-old male. Surgical removal confirmed the benign nature of this odontogenic neoplasm.

Keywords:
central dentinogenic ghost cell tumordgctgcocghost cell odontogenic carcinomaoncologypathologysurgery

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Area of Science:

  • Oral Pathology
  • Oncology

Background:

  • Odontogenic tumors are uncommon jaw neoplasms with diverse clinical behaviors.
  • Dentinogenic ghost cell tumors (DGCT) are rare odontogenic neoplasms, categorized as central (intraosseous) or peripheral (extraosseous).

Observation:

  • A central DGCT manifested as a painless, 3 × 5.3 cm expansile mass in the right mandibular body of a 66-year-old male patient.
  • The patient had multiple comorbidities and presented with the asymptomatic mandibular lesion.

Findings:

  • Radiographic and histologic assessments were performed.
  • Histopathology revealed classic DGCT features: ghost cells and calcifications.
  • A low proliferation index was noted, indicating low malignant potential.

Implications:

  • This case highlights the importance of recognizing central DGCT in the differential diagnosis of mandibular bone lesions.
  • Enucleation under local anesthesia proved effective for this benign odontogenic neoplasm.
  • Understanding DGCT's low malignant potential guides appropriate management strategies.