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Machine learning-based feature selection and classification for cerebral infarction screening: an experimental study.

Yang Niu1,2, Xue Tao3, Qinyuan Chang3

  • 1Department of Rehabilitation Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Peerj. Computer Science
|March 10, 2025
PubMed
Summary
This summary is machine-generated.

Machine learning enhances cerebral infarction screening using speech and cognitive data. The developed framework accurately identifies cerebral infarction and its subtypes, improving early detection.

Keywords:
Cerebral infarction screeningFeature selectionMachine learningSpeech and cognitive function assessment

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Area of Science:

  • Neurology
  • Artificial Intelligence
  • Medical Diagnostics

Background:

  • Cerebral infarction screening (CIS) is crucial for prompt treatment and better patient outcomes.
  • Machine learning (ML) offers potential for improving diagnostic accuracy in neurological conditions.

Purpose of the Study:

  • To develop and evaluate a machine learning framework (CIS) for enhanced cerebral infarction screening.
  • To utilize speech and cognitive function features for classifying cerebral infarction subtypes.

Main Methods:

  • Analysis of a dataset with 117 patients (cerebral infarction, lacunar infarction, healthy controls).
  • Application of Recursive Feature Elimination with Cross-Validation (RFECV) for feature selection.
  • Evaluation of various ML classifiers including XGBoost for binary and ternary classification.

Main Results:

  • The CIS framework achieved 88.89% accuracy in distinguishing cerebral infarction from controls.
  • The system reached 77.78% accuracy in classifying lacunar infarction, non-lacunar infarction, and healthy controls.
  • Selected speech and cognitive features proved significant for differentiating cerebral infarction subtypes.

Conclusions:

  • Machine learning effectively enhances cerebral infarction screening using speech and cognitive data.
  • The developed CIS framework shows promise for improving early detection and diagnosis of cerebral infarction subtypes.
  • Integration of ML into clinical practice could advance neurological diagnostics.