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Visual Assessment of Facial Differences in Patients Reconstructed With Ocular Prostheses: A Web-Based Survey
Akshita Wadhwa1,2,3, Pravin K Patel1,2,3, Linping Zhao1,2,3
1Department of Surgery, Division of Plastic, Cosmetic, and Reconstructive Surgery, The University of Illinois.
The Journal of Craniofacial Surgery
|March 10, 2025
Summary
Public raters could not distinguish prosthetic eyes from real eyes in a photo-based survey. This indicates a high success rate for ocular prostheses in mimicking natural eye appearance.
Area of Science:
- Ophthalmology
- Medical Aesthetics
- Reconstructive Surgery
Background:
- Facial differences in patients reconstructed with ocular prostheses compared to unaffected eyes.
- Hypothesis: Prosthetic eyes are indistinguishable from natural eyes.
Purpose of the Study:
- To determine the visual recognition of facial differences in patients with ocular prostheses.
- To assess the similarity or difference between prosthetic and contralateral unaffected eyes.
Main Methods:
- Randomized, local, photo-based survey.
- Five surveys with ten questions each, featuring photos of patients with prosthetic eye reconstruction.
- Participants identified prosthetic eyes from real eyes (A/B marking).
Main Results:
- Overall correctness (OA) was 38.4%, indicating difficulty in identifying prosthetic eyes.
- Average correctness per photo (CP) was below 50% for 69.4% of ratings.
- Raters could not reliably differentiate between prosthetic and natural eyes.
Conclusions:
- High consistency among respondents in discerning prosthetic from natural eyes.
- Prosthetic means achieve a high level of success in mimicking natural eye appearance.
- The study's hypothesis was proven.

